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WormBase Tree Display for Gene: WBGene00001978

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Name Class

WBGene00001978SMapS_parentSequenceR13H4
IdentityVersion1
NameCGC_namehmp-1Person_evidenceWBPerson498
Sequence_nameR13H4.4
Molecular_name (19)
Other_nameCELE_R13H4.4Accession_evidenceNDBBX284605
Public_namehmp-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhmp
Allele (102)
Legacy_information[C.elegansII] Mutations zygotic lethal, arrest at 1.25-1.5 fold stage with lumps in dorsal hypoderm. Cloned: encodes probable alpha-catenin homolog. [JJ]
StrainWBStrain00001826
WBStrain00022476
WBStrain00024213
WBStrain00030631
RNASeq_FPKM (74)
GO_annotation (27)
Ortholog (47)
ParalogWBGene00000832Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00000942Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
Structured_descriptionConcise_descriptionhmp-1 encodes an alpha-catenin; during development, hmp-1 activity is required for proper enclosure and elongation of the embryo; HMP-1 localizes to hypodermal adherens junctions.Paper_evidenceWBPaper00003046
Curator_confirmedWBPerson1843
Date_last_updated11 Jun 2008 00:00:00
Automated_descriptionEnables actin filament binding activity and beta-catenin binding activity. Involved in several processes, including cortical actin cytoskeleton organization; embryonic morphogenesis; and regulation of actin cytoskeleton organization. Located in adherens junction and apical junction complex. Part of catenin complex. Expressed in several structures, including distal tip cell; germ cell; intestinal cell; neuroblasts; and pharyngeal cell. Human ortholog(s) of this gene implicated in several diseases, including arrhythmogenic right ventricular dysplasia 13; cervix uteri carcinoma in situ; and urinary system cancer (multiple). Is an ortholog of human CTNNA2 (catenin alpha 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:8991Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2509)
DOID:11054Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2509)
DOID:0090131Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2510)
DOID:2671Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2509)
DOID:0060864Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2509)
DOID:0110084Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2511)
DOID:4450Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2509)
DOID:10283Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2509)
DOID:3457Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2509)
Molecular_infoCorresponding_CDSR13H4.4a
R13H4.4b
R13H4.4c
R13H4.4d
R13H4.4e
R13H4.4f
Corresponding_transcriptR13H4.4a.1
R13H4.4b.1
R13H4.4c.1
R13H4.4d.1
R13H4.4e.1
R13H4.4f.1
R13H4.4f.2
Other_sequence (49)
Associated_feature (11)
Experimental_infoRNAi_resultWBRNAi00077349Inferred_automaticallyRNAi_primary
WBRNAi00101412Inferred_automaticallyRNAi_primary
WBRNAi00063482Inferred_automaticallyRNAi_primary
WBRNAi00063488Inferred_automaticallyRNAi_primary
WBRNAi00063483Inferred_automaticallyRNAi_primary
WBRNAi00077347Inferred_automaticallyRNAi_primary
WBRNAi00101410Inferred_automaticallyRNAi_primary
WBRNAi00091282Inferred_automaticallyRNAi_primary
WBRNAi00077351Inferred_automaticallyRNAi_primary
WBRNAi00063484Inferred_automaticallyRNAi_primary
WBRNAi00093057Inferred_automaticallyRNAi_primary
WBRNAi00077352Inferred_automaticallyRNAi_primary
WBRNAi00101430Inferred_automaticallyRNAi_primary
WBRNAi00091281Inferred_automaticallyRNAi_primary
WBRNAi00051940Inferred_automaticallyRNAi_primary
WBRNAi00063487Inferred_automaticallyRNAi_primary
WBRNAi00091283Inferred_automaticallyRNAi_primary
WBRNAi00101428Inferred_automaticallyRNAi_primary
Expr_patternChronogram912
Expr6534
Expr9341
Expr13047
Expr14677
Expr1011130
Expr1031148
Expr1155584
Expr2012529
Expr2030768
Drives_constructWBCnstr00002622
WBCnstr00004619
WBCnstr00006235
WBCnstr00007873
WBCnstr00008029
WBCnstr00009117
WBCnstr00020495
WBCnstr00036545
Construct_productWBCnstr00020495
WBCnstr00036545
AntibodyWBAntibody00000167
WBAntibody00001450
WBAntibody00002691
Microarray_results (30)
Expression_cluster (135)
InteractionWBInteraction000002157
WBInteraction000002954
WBInteraction000003379
WBInteraction000009166
WBInteraction000009269
WBInteraction000029065
WBInteraction000030857
WBInteraction000030858
WBInteraction000034100
WBInteraction000050393
WBInteraction000052877
WBInteraction000126122
WBInteraction000126365
WBInteraction000126366
WBInteraction000126368
WBInteraction000126493
WBInteraction000126883
WBInteraction000142037
WBInteraction000142038
WBInteraction000149157
WBInteraction000150089
WBInteraction000161316
WBInteraction000235180
WBInteraction000275394
WBInteraction000283187
WBInteraction000304261
WBInteraction000308910
WBInteraction000309823
WBInteraction000310312
WBInteraction000341752
WBInteraction000354686
WBInteraction000358499
WBInteraction000360432
WBInteraction000362453
WBInteraction000363541
WBInteraction000369621
WBInteraction000372393
WBInteraction000375061
WBInteraction000381215
WBInteraction000381885
WBInteraction000395155
WBInteraction000398546
WBInteraction000414708
WBInteraction000417573
WBInteraction000431323
WBInteraction000439299
WBInteraction000440215
WBInteraction000441857
WBInteraction000442383
WBInteraction000443262
WBInteraction000452107
WBInteraction000454969
WBInteraction000455022
WBInteraction000461395
WBInteraction000461661
WBInteraction000501918
WBInteraction000501919
WBInteraction000502826
WBInteraction000503753
WBInteraction000504008
WBInteraction000518815
WBInteraction000518830
WBInteraction000520286
WBInteraction000520288
WBInteraction000522266
WBInteraction000539753
WBInteraction000540344
WBInteraction000540377
WBInteraction000540533
WBInteraction000540539
WBInteraction000542524
WBInteraction000542890
WBInteraction000543756
WBInteraction000543757
WBInteraction000543758
WBInteraction000543759
WBInteraction000543760
WBInteraction000543761
WBInteraction000543762
WBInteraction000543763
WBInteraction000543764
WBInteraction000543765
WBInteraction000543766
WBInteraction000543767
WBInteraction000543768
WBInteraction000543769
WBInteraction000543770
WBInteraction000543771
WBInteraction000543772
WBInteraction000543773
WBInteraction000543774
WBInteraction000551292
WBInteraction000553067
WBInteraction000555506
WBInteraction000555511
WBInteraction000555512
WBInteraction000555513
WBInteraction000555514
WBInteraction000555515
WBInteraction000555516
WBInteraction000555993
WBInteraction000556076
WBInteraction000557053
WBInteraction000557054
WBInteraction000557057
WBInteraction000557058
WBInteraction000557079
WBInteraction000557082
WBInteraction000557085
WBInteraction000557091
WBInteraction000559433
WBInteraction000574210
WBInteraction000575397
WBInteraction000579146
WBInteraction000579147
WBInteraction000579148
WBInteraction000579152
WBProcessWBbiopr:00000017
Map_infoMapVPosition3.46447Error0.012439
PositivePositive_cloneR13H4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4408
5036
Pseudo_map_position
Reference (108)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene