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WormBase Tree Display for Gene: HGNC:15781

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Name Class

HGNC:15781IdentityNameCGC_nameCHRFAM7AInferred_automaticallyAGR_import
Other_name (13)
Public_nameCHRFAM7A
DB_infoDatabaseHGNCid15781
AGRcURIHGNC:15781
EnsEMBLENSEMBL_geneIDENSG00000275917
ENSG00000274542
ENSG00000166664
ENSG00000175344
UniProtUniProt_ACQ494W8
P36544
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00000046Caenorhabditis elegansFrom_analysisOMA
OrthoFinder
Panther
PhylomeDB
WBGene00001133Caenorhabditis elegansFrom_analysisOrthoFinder
Panther
PhylomeDB
WBGene00000055Caenorhabditis elegansFrom_analysisHieranoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
WBGene00000048Caenorhabditis elegansFrom_analysisOrthoFinder
Panther
PhylomeDB
SonicParanoid
WBGene00000049Caenorhabditis elegansFrom_analysisOrthoFinder
Panther
PhylomeDB
WBGene00000050Caenorhabditis elegansFrom_analysisOMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
WBGene00000053Caenorhabditis elegansFrom_analysisOrthoFinder
Panther
PhylomeDB
WBGene00000054Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
Panther
PhylomeDB
WBGene00000058Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
Panther
PhylomeDB
WBGene00043066Caenorhabditis elegansFrom_analysisOrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionThe nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import