WormBase Tree Display for Gene: HGNC:15781
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HGNC:15781 | Identity | Name | CGC_name | CHRFAM7A | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Other_name (13) | ||||||
Public_name | CHRFAM7A | |||||
DB_info | Database | HGNC | id | 15781 | ||
AGR | cURI | HGNC:15781 | ||||
EnsEMBL | ENSEMBL_geneID | ENSG00000275917 | ||||
ENSG00000274542 | ||||||
ENSG00000166664 | ||||||
ENSG00000175344 | ||||||
UniProt | UniProt_AC | Q494W8 | ||||
P36544 | ||||||
Species | Homo sapiens | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00000046 | Caenorhabditis elegans | From_analysis | OMA | ||
OrthoFinder | ||||||
Panther | ||||||
PhylomeDB | ||||||
WBGene00001133 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
Panther | ||||||
PhylomeDB | ||||||
WBGene00000055 | Caenorhabditis elegans | From_analysis | Hieranoid | |||
OMA | ||||||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
PhylomeDB | ||||||
SonicParanoid | ||||||
WBGene00000048 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
Panther | ||||||
PhylomeDB | ||||||
SonicParanoid | ||||||
WBGene00000049 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
Panther | ||||||
PhylomeDB | ||||||
WBGene00000050 | Caenorhabditis elegans | From_analysis | OMA | |||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
PhylomeDB | ||||||
SonicParanoid | ||||||
WBGene00000053 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
Panther | ||||||
PhylomeDB | ||||||
WBGene00000054 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
OrthoFinder | ||||||
Panther | ||||||
PhylomeDB | ||||||
WBGene00000058 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
Inparanoid | ||||||
OrthoFinder | ||||||
Panther | ||||||
PhylomeDB | ||||||
WBGene00043066 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
OrthoInspector | ||||||
Panther | ||||||
PhylomeDB | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import |