WormBase Tree Display for Gene: RGD:2348
expand all nodes | collapse all nodes | view schema
| RGD:2348 | Identity | Name | CGC_name | Chrna7 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Chrna7 | |||||
| DB_info | Database | RGD | id | 2348 | ||
| AGR | cURI | RGD:2348 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000010853 | ||||
| UniProt | UniProt_AC | Q05941 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00000046 | Caenorhabditis elegans | From_analysis | OrthoFinder | ||
| Panther | ||||||
| PhylomeDB | ||||||
| WBGene00001133 | Caenorhabditis elegans | From_analysis | OMA | |||
| OrthoFinder | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| WBGene00000055 | Caenorhabditis elegans | From_analysis | Hieranoid | |||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00000048 | Caenorhabditis elegans | From_analysis | OMA | |||
| OrthoFinder | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00000049 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
| Panther | ||||||
| PhylomeDB | ||||||
| WBGene00000050 | Caenorhabditis elegans | From_analysis | OMA | |||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| WBGene00000053 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
| Panther | ||||||
| PhylomeDB | ||||||
| WBGene00000054 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
| OrthoFinder | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| WBGene00000058 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
| Inparanoid | ||||||
| OrthoFinder | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| WBGene00043066 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| Structured_description | Automated_description | Enables several functions, including acetylcholine binding activity; acetylcholine-gated monoatomic cation-selective channel activity; and enzyme binding activity. Involved in several processes, including neuronal action potential; regulation of ERK1 and ERK2 cascade; and synaptic signaling. Acts upstream of or within calcium ion transport and regulation of membrane potential. Located in several cellular components, including dendrite; growth cone; and plasma membrane raft. Part of acetylcholine-gated channel complex. Is active in several cellular components, including glycinergic synapse; spine apparatus membrane; and synaptic membrane. Used to study cognitive disorder. Biomarker of rheumatoid arthritis. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; esophagus squamous cell carcinoma; respiratory system cancer (multiple); and schizophrenia. Orthologous to human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; calcium/calcium-mediated signaling pathway; INTERACTS WITH (+)-Nornicotine; (S)-nicotine; 17alpha-ethynylestradiol. | Inferred_automatically | AGR_import |
