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WormBase Tree Display for Gene: WBGene00000422

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Name Class

WBGene00000422EvidenceCGC_data_submission
SMapS_parentSequenceF08F1
IdentityVersion1
NameCGC_nameced-8Person_evidenceWBPerson261
Sequence_nameF08F1.5
Molecular_nameF08F1.5
F08F1.5.1
CE34294
Other_nameCELE_F08F1.5Accession_evidenceNDBBX284606
Public_nameced-8
DB_infoDatabaseAceViewgeneXJ34
WormQTLgeneWBGene00000422
WormFluxgeneWBGene00000422
NDBlocus_tagCELE_F08F1.5
PanthergeneCAEEL|WormBase=WBGene00000422|UniProtKB=O17386
familyPTHR16024
NCBIgene184190
RefSeqproteinNM_077026.10
SwissProtUniProtAccO17386
TREEFAMTREEFAM_IDTF316454
UniProt_GCRPUniProtAccO17386
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classced
Allele (64)
Legacy_information[C.elegansII] n1891 : programmed cell deaths abnormal and protracted; dying cells arrest at highly refractile stage; killer cells fail to engulf target cells; superficially resembles engulfment group A (ced-1,6,7); but synergizes with weak ced-3 alleles in preventing cell death; no gross phenotype. OA3: n1999, n2090, n2093. Cloned: encodes predicted novel protein. [Ellis et al. 1991; MT]
StrainWBStrain00027186
WBStrain00027187
WBStrain00037401
RNASeq_FPKM (74)
GO_annotation (32)
Ortholog (52)
Structured_descriptionConcise_descriptionThe ced-8 gene encodes a homolog of the human putative membrane transporter XK; ced-8 is required for apoptosis to occur with normal speed during embryonic development.Paper_evidenceWBPaper00003983
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables phospholipid scramblase activity. Involved in apoptotic process; embryo development; and engulfment of apoptotic cell. Located in plasma membrane. Is an ortholog of human XKR6 (XK related 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF08F1.5
Corresponding_CDS_historyF08F1.5:wp102
Corresponding_transcriptF08F1.5.1
Other_sequenceAcan_isotig20595
Associated_featureWBsf654212
WBsf1006142
WBsf1006143
WBsf237679
Experimental_infoRNAi_resultWBRNAi00001054Inferred_automaticallyRNAi_primary
WBRNAi00044010Inferred_automaticallyRNAi_primary
WBRNAi00012898Inferred_automaticallyRNAi_primary
WBRNAi00012899Inferred_automaticallyRNAi_primary
WBRNAi00030650Inferred_automaticallyRNAi_primary
Expr_patternExpr11381
Expr1026179
Expr1030238
Expr1147977
Expr2009852
Expr2028092
Drives_constructWBCnstr00016070
WBCnstr00018810
WBCnstr00037554
Construct_productWBCnstr00018810
WBCnstr00037554
Microarray_results (19)
Expression_cluster (183)
Interaction (65)
WBProcessWBbiopr:00000014
WBbiopr:00000015
Map_infoMapXPosition-0.106284Error0.004973
Well_ordered
PositivePositive_cloneF08F1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point1571
1738
1739
1740
1741
1742
2211
4088
4755
Pos_neg_data4982
4983
4984
Reference (50)
RemarkSequence connection from [Stanfield GM]
MethodGene