WormBase Tree Display for Gene: WBGene00000585
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| WBGene00000585 | SMap | S_parent | Sequence | C06G3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cogc-2 | Paper_evidence | WBPaper00026979 | |||||
| Person_evidence | WBPerson449 | ||||||||
| Sequence_name | C06G3.10 | ||||||||
| Molecular_name | C06G3.10 | ||||||||
| C06G3.10.1 | |||||||||
| CE28817 | |||||||||
| Other_name | cog2 | Accession_evidence | EMBL | Z34976 | |||||
| cgo-2 | |||||||||
| CELE_C06G3.10 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | cogc-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 17 Jan 2006 13:29:50 | WBPerson2970 | Name_change | CGC_name | cogc-2 | ||||
| Other_name | cgo-2 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cogc | ||||||||
| Allele (33) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Contained_in_operon | CEOP4208 | ||||||||
| Ortholog (28) | |||||||||
| Structured_description | Concise_description | cogc-2 encodes an ortholog of mammalian COG-2, a subunit of lobe A ofthe conserved oligomeric Golgi complex (COGC); COGC-2 is required fornormal gonadal distal tip cell migration, a process that also requiresseven other orthologs of COGC subunits; like other lobe A subunits inboth C. elegans and S. cerevisiae, COGC-2 is strongly required fornormal function, while lobe B subunits are only partially required ineither worms or yeast. | Paper_evidence | WBPaper00026979 | |||||
| WBPaper00028363 | |||||||||
| WBPaper00028599 | |||||||||
| WBPaper00028603 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 25 Oct 2006 00:00:00 | ||||||||
| Automated_description | Involved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIq. Is an ortholog of human COG2 (component of oligomeric golgi complex 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070269 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6546) | ||||
| Molecular_info | Corresponding_CDS | C06G3.10 | |||||||
| Corresponding_transcript | C06G3.10.1 | ||||||||
| Other_sequence (23) | |||||||||
| Associated_feature | WBsf651882 | ||||||||
| WBsf981776 | |||||||||
| WBsf230214 | |||||||||
| WBsf230215 | |||||||||
| Experimental_info | RNAi_result (36) | ||||||||
| Expr_pattern | Expr1021050 | ||||||||
| Expr1030345 | |||||||||
| Expr1144006 | |||||||||
| Expr2010291 | |||||||||
| Expr2028533 | |||||||||
| Drives_construct | WBCnstr00037444 | ||||||||
| Construct_product | WBCnstr00037444 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (117) | |||||||||
| Interaction (19) | |||||||||
| Map_info | Map | IV | Position | 3.27829 | Error | 0.000592 | |||
| Positive | Positive_clone | C06G3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027766 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061547 | |||||||||
| Remark | C06G3.10 was incorrectly linked to cog-2. C06G3.10 is required for normal Golgi morphology and function and has nothing to do with cog - Connection Of Gonad defective. The EMBL gene name cog2 refers to a Golgi-localized protein complex. However, "cog" is not CGC approved | CGC_data_submission | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
