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WormBase Tree Display for Gene: WBGene00001086

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Name Class

WBGene00001086SMapS_parentSequenceR13G10
IdentityVersion1
NameCGC_namedpy-27Person_evidenceWBPerson261
Sequence_nameR13G10.1
Molecular_nameR13G10.1
R13G10.1.1
CE01052
Other_nameCELE_R13G10.1Accession_evidenceNDBBX284603
Public_namedpy-27
DB_infoDatabaseAceViewgene3E904
WormQTLgeneWBGene00001086
WormFluxgeneWBGene00001086
NDBlocus_tagCELE_R13G10.1
PanthergeneCAEEL|WormBase=WBGene00001086|UniProtKB=P48996
familyPTHR43939
NCBIgene175492
RefSeqproteinNM_065370.7
SwissProtUniProtAccP48996
TREEFAMTREEFAM_IDTF101158
UniProt_GCRPUniProtAccP48996
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:23WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdpy
Reference_alleleWBVar00275305
Allele (91)
Legacy_informationrh18mat : XX phenotype is zygotic weak dumpy maternal effect dumpy/near lethal like dpy-26 but non-Him. ES2. XO phenotype nearly wildtype male (ME3). NA1.
[C.elegansII] rh18mat : XX phenotype is zygotic weak dumpy maternal effect dumpy/near lethal like Dpy-26 but non-Him. ES2. XO phenotype nearly wildtype male (ME3). OA5: y57 (weaker allele), y44, y42, y56am, y49 (strongest allele). Cloned: encodes 1469 aa protein with similarities to chromosome structural proteins, specifically localized to X chromosomes in XX but not XO animals. [Plenefisch et al. 1989; Chuang et al. 1994]
StrainWBStrain00004518
WBStrain00004680
WBStrain00006374
WBStrain00029961
WBStrain00051718
WBStrain00054734
RNASeq_FPKM (74)
GO_annotation (21)
Ortholog (37)
ParalogWBGene00004874Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00001830Caenorhabditis elegansFrom_analysisPanther
WBGene00001860Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00003367Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004873Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00010306Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00012198Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016172Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00019087Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00044079Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptiondpy-27 encodes an ATP-binding protein that is a homolog of the SMC4 subunit of mitotic condensin; DPY-27, in combination with other proteins including MIX-1, act as a unit to repress X-linked gene expression during hermaphrodite dosage compensation; in XX oocytes and early embryos, DPY-27 exhibits diffuse nuclear localization, but by the 30-cell stage of embryogenesis, DPY-27 specifically localizes to X chromosomes; in XO animals at all stages, DPY-27 remains diffusely nuclear; the sex-specific localization of DPY-27 to X chromosomes is dependent upon wild-type activity of xol-1, as DPY-27 mislocalizes to the X chromosome of XO embryos in a xol-1 mutant background.Paper_evidenceWBPaper00002061
WBPaper00005173
WBPaper00005215
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated14 Mar 2006 00:00:00
Automated_descriptionEnables sequence-specific DNA binding activity. Involved in dosage compensation by hypoactivation of X chromosome. Located in X chromosome and nuclear chromosome. Part of dosage compensation complex. Is an ortholog of human SMC4 (structural maintenance of chromosomes 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSR13G10.1
Corresponding_transcriptR13G10.1.1
Other_sequenceFD516123.1
GO250655.1
SR04997
BXC07601_1
CSC01057_1
MJC03833_1
MJ04686
Associated_feature (15)
Gene_product_binds (205)
Transcription_factorWBTranscriptionFactor000139
Experimental_infoRNAi_result (26)
Expr_patternExpr1534
Expr4351
Expr8708
Expr1013736
Expr1030691
Expr1155578
Expr1200092
Expr2011068
Expr2029305
Drives_constructWBCnstr00020708
WBCnstr00037089
Construct_productWBCnstr00016736
WBCnstr00020708
WBCnstr00037089
Regulate_expr_clusterWBPaper00050193:dpy-27(RNAi)_downregulated_L1
WBPaper00050193:dpy-27(RNAi)_upregulated_L1
AntibodyWBAntibody00000633
WBAntibody00000970
WBAntibody00001231
WBAntibody00001460
WBAntibody00001592
WBAntibody00001731
WBAntibody00001961
Microarray_results (18)
Expression_cluster (148)
Interaction (183)
WBProcessWBbiopr:00000056
WBbiopr:00000099
Map_infoMapIIIPosition-4.25151Error0.000409
Well_ordered
PositivePositive_cloneC17A5
R13G10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point1612
Multi_point865
1639
2105
2106
2226
3205
4155
Pos_neg_data4706
ReferenceWBPaper00000941
WBPaper00001011
WBPaper00001013
WBPaper00001028
WBPaper00001077
WBPaper00001115
WBPaper00001116
WBPaper00001206
WBPaper00001279
WBPaper00001341
WBPaper00001659
WBPaper00001683
WBPaper00001691
WBPaper00001708
WBPaper00001772
WBPaper00001869
WBPaper00001955
WBPaper00001982
WBPaper00001991
WBPaper00002061
WBPaper00002074
WBPaper00002131
WBPaper00002278
WBPaper00002302
WBPaper00002303
WBPaper00002347
WBPaper00002605
WBPaper00002606
WBPaper00002631
WBPaper00002743
WBPaper00002765
WBPaper00003075
WBPaper00003279
WBPaper00003597
WBPaper00004130
WBPaper00004158
WBPaper00004443
WBPaper00004467
WBPaper00005173
WBPaper00005215
WBPaper00005221
WBPaper00005237
WBPaper00005272
WBPaper00005549
WBPaper00006355
WBPaper00006384
WBPaper00010744
WBPaper00013715
WBPaper00013718
WBPaper00013778
WBPaper00013841
WBPaper00013844
WBPaper00013953
WBPaper00014003
WBPaper00014084
WBPaper00014204
WBPaper00014205
WBPaper00014419
WBPaper00014783
WBPaper00014926
WBPaper00015147
WBPaper00016312
WBPaper00016313
WBPaper00016314
WBPaper00016419
WBPaper00016503
WBPaper00016556
WBPaper00017021
WBPaper00017056
WBPaper00017114
WBPaper00017243
WBPaper00017255
WBPaper00017260
WBPaper00017261
WBPaper00017324
WBPaper00017336
WBPaper00017413
WBPaper00017470
WBPaper00017475
WBPaper00017877
WBPaper00018402
WBPaper00018898
WBPaper00020769
WBPaper00020829
WBPaper00021109
WBPaper00021710
WBPaper00022128
WBPaper00022230
WBPaper00022499
WBPaper00022620
WBPaper00022885
WBPaper00022895
WBPaper00023040
WBPaper00023187
WBPaper00023328
WBPaper00023733
WBPaper00024044
WBPaper00024121
WBPaper00026779
WBPaper00027033
WBPaper00027240
WBPaper00027248
WBPaper00028816
WBPaper00028984
WBPaper00029117
WBPaper00030931
WBPaper00031121
WBPaper00031432
WBPaper00032180
WBPaper00032450
WBPaper00032533
WBPaper00033893
WBPaper00035408
WBPaper00035968
WBPaper00038180
WBPaper00038491
WBPaper00039724
WBPaper00040306
WBPaper00040685
WBPaper00047083
WBPaper00047160
WBPaper00047963
WBPaper00048375
WBPaper00048953
WBPaper00050935
WBPaper00053662
WBPaper00055090
WBPaper00057945
WBPaper00059616
WBPaper00062335
WBPaper00062532
WBPaper00063930
WBPaper00064630
WBPaper00064647
WBPaper00065841
MethodGene