WormBase Tree Display for Interaction: WBInteraction000542246
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| WBInteraction000542246 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003292 | Interactor_type | Trans_regulated | |
| WBGene00003309 | Interactor_type | Trans_regulated | |||
| WBGene00003308 | Interactor_type | Trans_regulated | |||
| WBGene00003293 | Interactor_type | Trans_regulated | |||
| WBGene00003281 | Interactor_type | Trans_regulated | |||
| WBGene00003286 | Interactor_type | Trans_regulated | |||
| WBGene00077722 | Interactor_type | Trans_regulated | |||
| WBGene00003328 | Interactor_type | Trans_regulated | |||
| Other_interactor | aging | Interactor_type | Trans_regulator | ||
| Interaction_summary | "To examine changes with age in animals lacking a germline, we collected individual glp-1 mutants spanning 4 adult ages that included both young and old animals (Figure 3A). Interestingly we found that expression from the mir-35-41 gene cluster was nearly absent in animals that lacked a gonad. Of the mir-35-41 cluster we only detected mir-37 in the germline ablated animals, but only in 30% of the individual worm samples. The levels of mir-37 we measured were much lower than those observed in wild type young adult animals (Figure 2F and compare Supplemental Tables 1 and 2)." | ||||
| Detection_method | RT_PCR | ||||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Negative_regulate | Life_stage | WBls:0000798 | ||
| Paper | WBPaper00042527 | ||||
| Remark | Fig. 2, 3, Table 2 |
