WormBase Tree Display for Variation: WBVar00142932
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WBVar00142932 | Name | Public_name | e47 | ||||||
---|---|---|---|---|---|---|---|---|---|
Sequence_details | SeqStatus | Pending_curation | |||||||
Variation_type | Allele | ||||||||
Origin | Species | Caenorhabditis elegans | |||||||
Strain | WBStrain00004084 | ||||||||
WBStrain00004543 | |||||||||
WBStrain00007120 | |||||||||
WBStrain00007985 | |||||||||
WBStrain00008442 | |||||||||
WBStrain00022535 | |||||||||
WBStrain00022537 | |||||||||
WBStrain00022541 | |||||||||
WBStrain00022590 | |||||||||
WBStrain00023657 | |||||||||
WBStrain00023815 | |||||||||
WBStrain00023816 | |||||||||
WBStrain00023817 | |||||||||
WBStrain00023818 | |||||||||
WBStrain00023825 | |||||||||
WBStrain00023826 | |||||||||
WBStrain00023954 | |||||||||
WBStrain00023955 | |||||||||
WBStrain00023956 | |||||||||
WBStrain00023957 | |||||||||
WBStrain00023961 | |||||||||
WBStrain00023966 | |||||||||
WBStrain00023967 | |||||||||
WBStrain00054788 | |||||||||
Laboratory | CB | ||||||||
Status | Live | ||||||||
Affects | Gene | WBGene00006751 | |||||||
Interactor | WBInteraction000500226 | ||||||||
WBInteraction000501652 | |||||||||
WBInteraction000555717 | |||||||||
WBInteraction000555718 | |||||||||
WBInteraction000555719 | |||||||||
WBInteraction000555720 | |||||||||
WBInteraction000555721 | |||||||||
WBInteraction000555724 | |||||||||
WBInteraction000555725 | |||||||||
Genetics | Mapping_data | In_2_point | 4 | ||||||
5 | |||||||||
2495 | |||||||||
3200 | |||||||||
3941 | |||||||||
5224 | |||||||||
6046 | |||||||||
6079 | |||||||||
6080 | |||||||||
6171 | |||||||||
In_multi_point (42) | |||||||||
In_pos_neg_data (21) | |||||||||
Description | Phenotype | WBPhenotype:0000017 | Paper_evidence | WBPaper00032011 | |||||
Person_evidence | WBPerson261 | ||||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Animals were resistant to 1mM aldicarb, as assayed by the % of animals paralyzed over time. | Paper_evidence | WBPaper00032011 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Ric | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Affected_by | Molecule | WBMol:00003650 | Paper_evidence | WBPaper00032011 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000019 | Paper_evidence | WBPaper00001709 | |||||||
Person_evidence | WBPerson261 | ||||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPerson712 | |||||||||
Remark | slow pharyngeal pumping | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0003681 | PATO:0000460 | Paper_evidence | WBPaper00001709 | ||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0000020 | Paper_evidence | WBPaper00001709 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0003681 | PATO:0000460 | Paper_evidence | WBPaper00001709 | ||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0000153 | Paper_evidence | WBPaper00032190 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Animals exhibited increased contractions. | Paper_evidence | WBPaper00032190 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Genotype | zxIs6 | Paper_evidence | WBPaper00032190 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000164 | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | slightly thin | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000229 | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | slightly small | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000315 | Paper_evidence | WBPaper00046308 | |||||||
Curator_confirmed | WBPerson10425 | ||||||||
WBPhenotype:0000352 | Paper_evidence | WBPaper00001709 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | Jerky backward motion | Paper_evidence | WBPaper00001709 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0000420 | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | hypersensitive to levamisole | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000436 | Paper_evidence | WBPaper00028886 | |||||||
Curator_confirmed | WBPerson48 | ||||||||
Remark | Localization of the synaptic protein SNB-1 is abnormal, based on expression analysis of SNB-1::VENUS; expression appears diffuse across the plasma membrane. | Paper_evidence | WBPaper00028886 | ||||||
Curator_confirmed | WBPerson48 | ||||||||
WBPhenotype:0000507 | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | elevated acetylcholine levels | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000544 | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | kinker, jerky ratchet-like movement especially in reverse | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Ease_of_scoring | ES3_Easy_to_score | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000594 | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Some migration defects. | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000616 | Paper_evidence | WBPaper00025079 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | GLR-1::GFP puncta intensity and width were significantly different from those in wild-type animals. | Paper_evidence | WBPaper00025079 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000643 | Paper_evidence | WBPaper00000031 | |||||||
Curator_confirmed | WBPerson48 | ||||||||
WBPhenotype:0000679 | Paper_evidence | WBPaper00005349 | |||||||
Curator_confirmed | WBPerson10038 | ||||||||
Remark | quoted from paper: "in a screen for mutants that have increased abundance of GLR-1::GFP in the ventral nerve cord (data not shown). Similar defects in GLR-1::GFP abundance were observed in other unc-11 mutants, including strains carrying the putative null allele, e47 (Figure 2)." Figure 2 title: " Mutants Lacking unc-11 AP180 Had Increased Abundance of GLR-1::GFP in the Ventral Nerve Cord" | Paper_evidence | WBPaper00005349 | ||||||
Curator_confirmed | WBPerson10038 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0005829 | PATO:0000460 | Paper_evidence | WBPaper00005349 | ||||
Curator_confirmed | WBPerson10038 | ||||||||
Phenotype_assay | Genotype | nuIs24 [GLR-1::GFP] | Paper_evidence | WBPaper00005349 | |||||
Curator_confirmed | WBPerson10038 | ||||||||
Phenotype_not_observed | WBPhenotype:0000306 | Paper_evidence | WBPaper00032190 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Expression of ChR2-YFP in cholinergic neurons was not affected. | Paper_evidence | WBPaper00032190 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Genotype | zxIs6 | Paper_evidence | WBPaper00032190 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000679 | Paper_evidence | WBPaper00028448 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | The unc-11(e47) mutation does not alter PKD-2 localization to the dendrite or cilium. | Paper_evidence | WBPaper00028448 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001426 | Paper_evidence | WBPaper00004883 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Variation_effect | Null | Paper_evidence | WBPaper00004883 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Genotype | arIs37 | Paper_evidence | WBPaper00004883 | |||||
Curator_confirmed | WBPerson712 | ||||||||
Reference (15) | |||||||||
Remark | |||||||||
Method | Allele |