WormBase Tree Display for Expression_cluster: WBPaper00037950:dopaminergic-neurons_CoreEnriched

WBPaper00037950:dopaminergic-neurons_CoreEnriched Description: Genes significantly enriched (> 2x, FDR < 5%) in a particular cell-type versus a reference sample of all cells at both embryonic and larval stages.
  Species: Caenorhabditis elegans
  Algorithm: A Mann-Whitney U test with an empirical background model and FDR correction for multiple testing was used to detect expressed transcripts (Benjamini and Hochberg 1995). Genes and TARs with an FDR <= 0.05 were reported as expressed above background. Authors detected differentially expressed transcripts using a method based on linear models. Genes and TARs were called differentially expressed if the FDR was <= 0.05 and the fold change (FC) >= 2.0. To more strictly correct for potential false-positives resulting from multiple sample comparisons, authors divided individual FDR estimates by the number of samplesor sample comparisons, respectively. This resulted in an adjusted FDR of 1.3 * 0.0001 for expression above background and of 7.4 * 0.0001 for differential expression. Authors called genes selectively enriched in a given tissue if they met the following requirements: (1) enriched expression in a given tissue (FDR <= 0.05 and FC >= 2.0), (2) fold change versus reference among the upper 40% of the positive FC range observed for this gene across all tissues, and (3) fold-change entropy among the lower 40% of the distribution observed for all genes.
  Reference: WBPaper00037950
  Based_on_WB_Release: 199
  Gene: WBGene00022664
    WBGene00012281
    WBGene00001127
    WBGene00000135
    WBGene00017042
    WBGene00022465
    WBGene00016801
    WBGene00001594
    WBGene00012289
    WBGene00011630
    WBGene00015664
    WBGene00019057
    WBGene00008255
    WBGene00010059
    WBGene00010349
    WBGene00000174
    WBGene00018043
    WBGene00011732
    WBGene00017980
    WBGene00001447
    WBGene00020323
    WBGene00007374
    WBGene00014175
    WBGene00003748
    WBGene00000295
    WBGene00009387
    WBGene00012132
    WBGene00020502
    WBGene00019324
    WBGene00000296
    WBGene00022786
    WBGene00019875
    WBGene00020010
    WBGene00007810
    WBGene00020444
    WBGene00006774
    WBGene00019765
    WBGene00008438
    WBGene00010916
    WBGene00021388
    WBGene00005558
    WBGene00013415
    WBGene00022419
    WBGene00005557
    WBGene00018639
    WBGene00011398
    WBGene00018281
    WBGene00010335
    WBGene00008570
    WBGene00000244
    WBGene00020726
    WBGene00007664
    WBGene00045336
    WBGene00016627
    WBGene00000934
    WBGene00020163
    WBGene00013534
    WBGene00016911
    WBGene00015539
    WBGene00014074
    WBGene00015866
    WBGene00012178
    WBGene00015018
    WBGene00008819
    WBGene00044509
    WBGene00010538
    WBGene00022815
    WBGene00016935
    WBGene00006538
    WBGene00022392
    WBGene00016005
    WBGene00043992
    WBGene00017741
    WBGene00018582
    WBGene00013273
    WBGene00003732
    WBGene00012779
    WBGene00006535
    WBGene00008521
    WBGene00008407
    WBGene00001117
    WBGene00020657
    WBGene00021123
    WBGene00017394
    WBGene00003885
    WBGene00023414
    WBGene00006749
    WBGene00013028
    WBGene00000492
    WBGene00011217
    WBGene00044144
    WBGene00007849
    WBGene00003232
    WBGene00000484
    WBGene00017297
    WBGene00010683
    WBGene00016938
    WBGene00021395
    WBGene00004798
    WBGene00020196
    WBGene00001709
    WBGene00006066
    WBGene00000059
    WBGene00011586
    WBGene00017973
    WBGene00013970
    WBGene00009484
    WBGene00018879
    WBGene00044701
    WBGene00044756
    WBGene00009742
    WBGene00018880
    WBGene00020573
    WBGene00010970
    WBGene00005641
    WBGene00012042
    WBGene00007490
    WBGene00017039
    WBGene00001987
    WBGene00001053
    WBGene00009757
    WBGene00000239
    WBGene00000284
    WBGene00000298
    WBGene00000403
    WBGene00000463
    WBGene00000490
    WBGene00000914
    WBGene00000995
    WBGene00001121
    WBGene00001440
    WBGene00001452
    WBGene00003657
    WBGene00003883
    WBGene00003886
    WBGene00004793
    WBGene00004921
    WBGene00006752
    WBGene00006831
    WBGene00006960
    WBGene00006999
    WBGene00008128
    WBGene00008226
    WBGene00008956
    WBGene00010974
    WBGene00011966
    WBGene00016289
    WBGene00018514
    WBGene00020368
    WBGene00044330
  Attribute_of: Tiling_array
  Associated_with: Life_stage: WBls:0000003
      WBls:0000023
    Anatomy_term: WBbt:0006746 Enriched
        mRNA_tagging