WormBase Tree Display for Gene: WBGene00001086
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| WBGene00001086 | SMap | S_parent | Sequence | R13G10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | dpy-27 | Person_evidence | WBPerson261 | |||||
| Sequence_name | R13G10.1 | ||||||||
| Molecular_name | R13G10.1 | ||||||||
| R13G10.1.1 | |||||||||
| CE01052 | |||||||||
| Other_name | CELE_R13G10.1 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | dpy-27 | ||||||||
| DB_info | Database | AceView | gene | 3E904 | |||||
| WormQTL | gene | WBGene00001086 | |||||||
| WormFlux | gene | WBGene00001086 | |||||||
| NDB | locus_tag | CELE_R13G10.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001086|UniProtKB=P48996 | |||||||
| family | PTHR43939 | ||||||||
| NCBI | gene | 175492 | |||||||
| RefSeq | protein | NM_065370.7 | |||||||
| SwissProt | UniProtAcc | P48996 | |||||||
| TREEFAM | TREEFAM_ID | TF101158 | |||||||
| UniProt_GCRP | UniProtAcc | P48996 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dpy | ||||||||
| Reference_allele | WBVar00275305 | ||||||||
| Allele (91) | |||||||||
| Legacy_information | rh18mat : XX phenotype is zygotic weak dumpy maternal effect dumpy/near lethal like dpy-26 but non-Him. ES2. XO phenotype nearly wildtype male (ME3). NA1. | ||||||||
| [C.elegansII] rh18mat : XX phenotype is zygotic weak dumpy maternal effect dumpy/near lethal like Dpy-26 but non-Him. ES2. XO phenotype nearly wildtype male (ME3). OA5: y57 (weaker allele), y44, y42, y56am, y49 (strongest allele). Cloned: encodes 1469 aa protein with similarities to chromosome structural proteins, specifically localized to X chromosomes in XX but not XO animals. [Plenefisch et al. 1989; Chuang et al. 1994] | |||||||||
| Strain | WBStrain00004518 | ||||||||
| WBStrain00004680 | |||||||||
| WBStrain00006374 | |||||||||
| WBStrain00029961 | |||||||||
| WBStrain00051718 | |||||||||
| WBStrain00054734 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00004874 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001830 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00001860 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00003367 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00004873 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00010306 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00012198 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00016172 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00019087 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00044079 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | dpy-27 encodes an ATP-binding protein that is a homolog of the SMC4 subunit of mitotic condensin; DPY-27, in combination with other proteins including MIX-1, act as a unit to repress X-linked gene expression during hermaphrodite dosage compensation; in XX oocytes and early embryos, DPY-27 exhibits diffuse nuclear localization, but by the 30-cell stage of embryogenesis, DPY-27 specifically localizes to X chromosomes; in XO animals at all stages, DPY-27 remains diffusely nuclear; the sex-specific localization of DPY-27 to X chromosomes is dependent upon wild-type activity of xol-1, as DPY-27 mislocalizes to the X chromosome of XO embryos in a xol-1 mutant background. | Paper_evidence | WBPaper00002061 | |||||
| WBPaper00005173 | |||||||||
| WBPaper00005215 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 14 Mar 2006 00:00:00 | ||||||||
| Automated_description | Enables sequence-specific DNA binding activity. Involved in dosage compensation by hypoactivation of X chromosome. Located in X chromosome and nuclear chromosome. Part of dosage compensation complex. Is an ortholog of human SMC4 (structural maintenance of chromosomes 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | R13G10.1 | |||||||
| Corresponding_transcript | R13G10.1.1 | ||||||||
| Other_sequence | FD516123.1 | ||||||||
| GO250655.1 | |||||||||
| SR04997 | |||||||||
| BXC07601_1 | |||||||||
| CSC01057_1 | |||||||||
| MJC03833_1 | |||||||||
| MJ04686 | |||||||||
| Associated_feature (15) | |||||||||
| Gene_product_binds (205) | |||||||||
| Transcription_factor | WBTranscriptionFactor000139 | ||||||||
| Experimental_info | RNAi_result (26) | ||||||||
| Expr_pattern | Expr1534 | ||||||||
| Expr4351 | |||||||||
| Expr8708 | |||||||||
| Expr1013736 | |||||||||
| Expr1030691 | |||||||||
| Expr1155578 | |||||||||
| Expr1200092 | |||||||||
| Expr2011068 | |||||||||
| Expr2029305 | |||||||||
| Drives_construct | WBCnstr00020708 | ||||||||
| WBCnstr00037089 | |||||||||
| Construct_product | WBCnstr00016736 | ||||||||
| WBCnstr00020708 | |||||||||
| WBCnstr00037089 | |||||||||
| Regulate_expr_cluster | WBPaper00050193:dpy-27(RNAi)_downregulated_L1 | ||||||||
| WBPaper00050193:dpy-27(RNAi)_upregulated_L1 | |||||||||
| Antibody | WBAntibody00000633 | ||||||||
| WBAntibody00000970 | |||||||||
| WBAntibody00001231 | |||||||||
| WBAntibody00001460 | |||||||||
| WBAntibody00001592 | |||||||||
| WBAntibody00001731 | |||||||||
| WBAntibody00001961 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (148) | |||||||||
| Interaction (183) | |||||||||
| WBProcess | WBbiopr:00000056 | ||||||||
| WBbiopr:00000099 | |||||||||
| Map_info | Map | III | Position | -4.25151 | Error | 0.000409 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | C17A5 | |||||||
| R13G10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Mapping_data | 2_point | 1612 | |||||||
| Multi_point | 865 | ||||||||
| 1639 | |||||||||
| 2105 | |||||||||
| 2106 | |||||||||
| 2226 | |||||||||
| 3205 | |||||||||
| 4155 | |||||||||
| Pos_neg_data | 4706 | ||||||||
| Reference (135) | |||||||||
| Method | Gene |
