WormBase Tree Display for Gene: WBGene00000053

WBGene00000053 SMap: S_parent: Sequence: T05C12
  Identity: Version: 1
    Name: CGC_name: acr-14 Person_evidence: WBPerson1430
      Sequence_name: T05C12.2
      Molecular_name: T05C12.2
        T05C12.2.1
        CE25099
      Other_name: CELE_T05C12.2 Accession_evidence: NDB BX284602
      Public_name: acr-14
    DB_info: Database: AceView gene 2I462
        WormQTL gene WBGene00000053
        WormFlux gene WBGene00000053
        NDB locus_tag CELE_T05C12.2
        Panther gene CAEEL|WormBase=WBGene00000053|UniProtKB=Q22224
          family PTHR18945
        NCBI gene 191601
        RefSeq protein NM_063315.3
        TrEMBL UniProtAcc Q22224
        UniProt_GCRP UniProtAcc Q22224
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:19 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: acr
    Allele (30)
    Strain: WBStrain00031836
    RNASeq_FPKM (74)
    GO_annotation (28)
    Ortholog: WBGene00053805 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00024072 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00147758 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00190745 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      CBOVI.g6368 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g3130 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g6461 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g12817 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g6427 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g9410 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g9450 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g2225 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g6632 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g19260 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      CSP40.g19261 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-acr-14 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g18519 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp11.Scaffold630.g21277 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00451.g11547 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_08771 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_005080 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g07670 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_20154320 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g5179 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00183093 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00114769 Pristionchus pacificus From_analysis: WormBase-Compara
      FB:FBgn0086778 Drosophila melanogaster From_analysis: OrthoFinder
            Panther
            PhylomeDB
      FB:FBgn0032151 Drosophila melanogaster From_analysis: OrthoFinder
            Panther
            PhylomeDB
      FB:FBgn0028875 Drosophila melanogaster From_analysis: OrthoFinder
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-040108-3 Danio rerio From_analysis: OrthoFinder
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-060503-606 Danio rerio From_analysis: OrthoFinder
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-090313-161 Danio rerio From_analysis: OrthoFinder
            Panther
            PhylomeDB
      HGNC:1960 Homo sapiens From_analysis: OrthoFinder
            Panther
            PhylomeDB
      HGNC:15781 Homo sapiens From_analysis: OrthoFinder
            Panther
            PhylomeDB
      MGI:99779 Mus musculus From_analysis: OrthoFinder
            Panther
            PhylomeDB
      RGD:2348 Rattus norvegicus From_analysis: OrthoFinder
            Panther
            PhylomeDB
    Paralog: WBGene00000042 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000043 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000044 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000045 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000046 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000047 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000048 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000049 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000050 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000051 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00006784 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001586 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001587 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001588 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000233 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00002974 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00006765 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00006774 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000951 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001133 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00006797 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00001591 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001592 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001593 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00008280 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009799 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00010275 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00010741 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018880 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000058 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00001512 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000060 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000055 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000061 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000955 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00002975 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00017580 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000056 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00043066 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000059 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00019069 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00015412 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00022247 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000054 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00020048 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00017375 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00010994 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00021981 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000057 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00012857 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000062 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00013534 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00008997 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00020836 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00017389 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00008551 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000845 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00007903 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00007191 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00022283 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00011360 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00011359 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00011358 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00013655 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00011356 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00011355 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020236 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00011354 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00045385 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00007594 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00044301 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00017543 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00017544 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00013338 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00013300 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020528 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00013517 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000232 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020767 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00021146 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00022106 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00008223 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020657 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00013746 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00008076 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00008022 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00017314 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00021437 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009790 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003386 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020605 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001594 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00017399 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020569 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012099 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00013914 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001373 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012915 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00017483 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00044528 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: acr-14 encodes a protein that contains neurotransmitter-gated ion-channel ligand-binding and transmembrane domains. Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in intestine; muscle cell; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1960)
      DOID:3908 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1960)
      DOID:3748 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1960)
      DOID:8778 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1960)
      DOID:3083 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1960)
      DOID:12217 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1960)
      DOID:8577 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1960)
      DOID:1324 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1960)
      DOID:7474 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1960)
      DOID:5419 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1960)
  Molecular_info: Corresponding_CDS: T05C12.2
    Corresponding_transcript: T05C12.2.1
    Other_sequence: JI180092.1
    Associated_feature: WBsf223455
      WBsf223456
  Experimental_info: RNAi_result: WBRNAi00066388 Inferred_automatically: RNAi_primary
      WBRNAi00097922 Inferred_automatically: RNAi_primary
      WBRNAi00052489 Inferred_automatically: RNAi_primary
      WBRNAi00018218 Inferred_automatically: RNAi_primary
      WBRNAi00078345 Inferred_automatically: RNAi_primary
      WBRNAi00035191 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1906
      Expr4858
      Expr8203
      Expr10607
      Expr13428
      Expr1018728
      Expr1156115
      Expr2009181
      Expr2027420
    Drives_construct (11)
    Construct_product: WBCnstr00016680
      WBCnstr00037766
    Microarray_results (20)
    Expression_cluster (91)
    Interaction (28)
  Map_info (4)
  Reference (26)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene