WormBase Tree Display for Expression_cluster: WBPaper00040210:Chlorpyrifos_24C_regulated

WBPaper00040210:Chlorpyrifos_24C_regulated Description: Genes with differential expression under 0.5mg/l Chlorpyrifos (CPF) treatment at 24 centigrade.
  Species: Caenorhabditis elegans
  Algorithm: To identify the differentially expressed genes in each treatment authors used linear models per toxicant and temperature (gene expression = Toxicant (effect) + error). The lm function in R stats package was used to implement the linear models analysis with recommended default options. For threshold determination authors used a permutation approach. For each of the 23,232 permutations used authors randomly picked a transcript (array spot), which could only be picked once. Authors combined all the expression values of this transcript and randomly distributed them over the replicates and used them in the linear model. In this way authors obtained a threshold for each of the toxicants. Authors used a -log10 p-value 2 as common threshold for the analysis, which resembles to the following FDR per toxicant: 0.0155 for CPF at 24 centigrade, 0.0148 for DZN at 24 centigrade, 0.0168 for CPF+DZN at 24 centigrade, 0.0142 for CPF at 16 centigrade, 0.0151 for DZN at 16 centigrade, and 0.0148 for CPF+DZN, at 16 centigrade.
  Reference: WBPaper00040210
  Microarray_results: cea2.i.25168 P value: 2.00E-06.
    cea2.p.135278 P value: 1.50E-05.
    cea2.d.13135 P value: 1.70E-05.
    cea2.p.94728 P value: 2.10E-05.
    cea2.c.46743 P value: 3.20E-05.
    cea2.c.45189 P value: 3.90E-05.
    cea2.p.120260 P value: 4.20E-05.
    cea2.p.55976 P value: 4.40E-05.
    cea2.c.28617 P value: 4.70E-05.
    cea2.i.65537 P value: 4.70E-05.
    cea2.3.28052 P value: 5.80E-05.
    cea2.i.20795 P value: 6.20E-05.
    cea2.d.38988 P value: 9.10E-05.
    cea2.c.29371 P value: 9.20E-05.
    cea2.p.149606 P value: 9.40E-05.
    cea2.i.42644 P value: 9.70E-05.
    cea2.p.08054 P value: 0.000105.
    cea2.p.107596 P value: 0.000106.
    cea2.d.00753 P value: 0.000106.
    cea2.d.30978 P value: 0.000108.
    cea2.3.08897 P value: 0.000112.
    cea2.p.138876 P value: 0.000113.
    cea2.p.31733 P value: 0.000117.
    cea2.p.15236 P value: 0.000121.
    cea2.p.116461 P value: 0.000123.
    cea2.c.16055 P value: 0.000125.
    cea2.p.93077 P value: 0.000127.
    cea2.d.24400 P value: 0.000134.
    cea2.p.120263 P value: 0.000142.
    cea2.p.11788 P value: 0.000157.
    cea2.p.125110 P value: 0.000158.
    cea2.p.126273 P value: 0.000158.
    cea2.i.25609 P value: 0.000165.
    cea2.c.31565 P value: 0.000165.
    cea2.p.27059 P value: 0.000176.
    cea2.c.48369 P value: 0.000181.
    cea2.d.08480 P value: 0.000192.
    cea2.d.43764 P value: 0.000196.
    cea2.i.44641 P value: 0.000202.
    cea2.i.59961 P value: 0.00022.
    cea2.p.94039 P value: 0.000224.
    cea2.3.08059 P value: 0.000226.
    cea2.i.11313 P value: 0.000227.
    cea2.i.06541 P value: 0.00023.
    cea2.i.12307 P value: 0.000232.
    cea2.c.38308 P value: 0.000251.
    cea2.d.19480 P value: 0.000257.
    cea2.d.06592 P value: 0.00026.
    cea2.c.24046 P value: 0.00027.
    cea2.p.106691 P value: 0.000272.
    cea2.i.46562 P value: 0.000272.
    cea2.c.04042 P value: 0.000278.
    cea2.p.10425 P value: 0.000298.
    cea2.p.111402 P value: 0.000301.
    cea2.i.40394 P value: 0.000305.
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    cea2.p.34951 P value: 0.00034.
    cea2.i.15677 P value: 0.000362.
    cea2.i.04780 P value: 0.000363.
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    cea2.c.30515 P value: 0.000381.
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    cea2.c.25054 P value: 0.000388.
    cea2.p.56287 P value: 0.000403.
    cea2.p.115587 P value: 0.000414.
    cea2.i.46522 P value: 0.00042.
    cea2.i.05527 P value: 0.000427.
    cea2.p.23625 P value: 0.000434.
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    cea2.p.128530 P value: 0.000441.
    cea2.p.112529 P value: 0.000458.
    cea2.i.34283 P value: 0.00046.
    cea2.p.117364 P value: 0.00046.
    cea2.d.25137 P value: 0.000461.
    cea2.p.112183 P value: 0.00047.
    cea2.d.37425 P value: 0.000472.
    cea2.p.49651 P value: 0.000472.
    cea2.p.129451 P value: 0.000475.
    cea2.d.32140 P value: 0.000486.
    cea2.f.08178 P value: 0.000487.
    cea2.3.30024 P value: 0.000493.
    cea2.p.101034 P value: 0.000496.
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    cea2.p.109594 P value: 0.000556.
    cea2.d.06538 P value: 0.000556.
    cea2.c.06362 P value: 0.000599.
    cea2.i.12977 P value: 0.000601.
    cea2.p.132317 P value: 0.000603.
    cea2.d.07199 P value: 0.000624.
    cea2.p.113263 P value: 0.000634.
    cea2.p.87872 P value: 0.000637.
    cea2.p.139449 P value: 0.000656.
    cea2.i.54821 P value: 0.000669.
    cea2.i.18457 P value: 0.000675.
    cea2.i.08455 P value: 0.000686.
    cea2.i.34701 P value: 0.000699.
    cea2.p.117933 P value: 0.000721.
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    cea2.d.43660 P value: 0.000732.
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    cea2.p.20029 P value: 0.000867.
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    cea2.p.48991 P value: 0.000896.
    cea2.p.99739 P value: 9.00E-04.
    cea2.d.03943 P value: 0.000905.
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    cea2.p.55566 P value: 0.000944.
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    cea2.c.21233 P value: 0.000954.
    cea2.d.13075 P value: 0.000956.
    cea2.i.47686 P value: 0.000956.
    cea2.i.22226 P value: 0.000959.
    cea2.p.115997 P value: 0.000966.
    cea2.p.134913 P value: 0.000974.
    cea2.c.26820 P value: 0.000976.
    cea2.i.30269 P value: 0.000977.
    cea2.3.04056 P value: 0.000981.
    cea2.c.44880 P value: 0.000988.
    cea2.p.43481 P value: 0.00099.
    cea2.c.28966 P value: 0.000998.
    cea2.i.13263 P value: 0.001002.
    cea2.p.80054 P value: 0.001006.
    cea2.i.16937 P value: 0.001007.
    cea2.i.24881 P value: 0.001011.
    cea2.i.37076 P value: 0.001022.
    cea2.d.47689 P value: 0.001022.
    cea2.d.25466 P value: 0.001029.
    cea2.c.13977 P value: 0.001029.
    cea2.d.15349 P value: 0.00103.
    cea2.p.07746 P value: 0.001056.
    cea2.3.15332 P value: 0.001061.
    cea2.d.19628 P value: 0.001082.
    cea2.d.07827 P value: 0.001094.
    cea2.i.50879 P value: 0.001121.
    cea2.p.73091 P value: 0.001123.
    cea2.c.06440 P value: 0.001127.
    cea2.p.43984 P value: 0.001153.
    cea2.c.06397 P value: 0.001157.
    cea2.d.24911 P value: 0.001165.
    cea2.p.21155 P value: 0.001178.
    cea2.d.06050 P value: 0.001184.
    cea2.d.21967 P value: 0.001194.
    cea2.p.150939 P value: 0.001208.
    cea2.3.23199 P value: 0.001211.
    cea2.c.35288 P value: 0.001218.
    cea2.p.77081 P value: 0.00122.
    cea2.p.112566 P value: 0.001241.
    cea2.d.00017 P value: 0.001242.
    cea2.c.24150 P value: 0.001246.
    cea2.d.06371 P value: 0.00125.
    cea2.c.44977 P value: 0.00127.
    cea2.d.30654 P value: 0.001279.
    cea2.p.105809 P value: 0.001282.
    cea2.p.115910 P value: 0.001288.
    cea2.i.62690 P value: 0.001295.
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    cea2.i.42489 P value: 0.001386.
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    cea2.p.99176 P value: 0.001414.
    cea2.3.22412 P value: 0.001427.
    cea2.i.21804 P value: 0.001429.
    cea2.p.107923 P value: 0.001447.
    cea2.p.27968 P value: 0.001451.
    cea2.p.130662 P value: 0.001469.
    cea2.p.140361 P value: 0.001471.
    cea2.i.53554 P value: 0.001473.
    cea2.d.08013 P value: 0.001493.
    cea2.c.23340 P value: 0.001502.
    cea2.d.23992 P value: 0.001507.
    cea2.p.157756 P value: 0.001513.
    cea2.c.21767 P value: 0.001514.
    cea2.d.03558 P value: 0.001526.
    cea2.c.07603 P value: 0.001529.
    cea2.i.38305 P value: 0.001546.
    cea2.p.00142 P value: 0.001557.
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    cea2.i.09558 P value: 0.001582.
    cea2.3.16707 P value: 0.001583.
    cea2.c.30170 P value: 0.00159.
    cea2.c.27723 P value: 0.001603.
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    cea2.c.48606 P value: 0.001619.
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    cea2.i.32192 P value: 0.001656.
    cea2.i.42786 P value: 0.001663.
    cea2.p.158350 P value: 0.001663.
    cea2.3.29112 P value: 0.001681.
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    cea2.p.83721 P value: 0.001688.
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    WBGene00015878
    WBGene00021329
    WBGene00018616
    WBGene00016082
    WBGene00001023
    WBGene00013530
    WBGene00002073
    WBGene00007420
    WBGene00010831
    WBGene00019481
    WBGene00003671
    WBGene00003911
    WBGene00021779
    WBGene00009605
    WBGene00019736
    WBGene00000930
    WBGene00004398
    WBGene00020007
    WBGene00012339
    WBGene00001951
    WBGene00004183
    WBGene00007630
    WBGene00010480
    WBGene00009483
    WBGene00011143
    WBGene00000111
    WBGene00004206
    WBGene00013258
    WBGene00007816
    WBGene00011942
    WBGene00021817
    WBGene00009783
    WBGene00009956
    WBGene00011491
    WBGene00002125
    WBGene00001152
    WBGene00003856
    WBGene00003548
    WBGene00001451
    WBGene00010251
    WBGene00007947
    WBGene00005073
    WBGene00020507
    WBGene00022824
    WBGene00003792
    WBGene00011850
    WBGene00009513
    WBGene00015540
    WBGene00020970
    WBGene00008788
    WBGene00004058
    WBGene00020727
    WBGene00006129
    WBGene00007578
    WBGene00009414
    WBGene00019886
    WBGene00009666
    WBGene00008127
    WBGene00015171
    WBGene00018161
    WBGene00006561
    WBGene00010307
    WBGene00010665
    WBGene00001578
    WBGene00007666
    WBGene00019841
    WBGene00012747
    WBGene00019598
    WBGene00011120
    WBGene00004109
    WBGene00000773
  Attribute_of: Microarray_experiment: WBPaper00040210:Control_vs_CPF-(0.5)_Rep1
      WBPaper00040210:Control_vs_CPF-(0.5)_Rep2
      WBPaper00040210:Control_vs_CPF-(0.5)_Rep3
      WBPaper00040210:CPF-(0.5)_vs_Control_Rep1
      WBPaper00040210:CPF-(0.5)_vs_Control_Rep2
      WBPaper00040210:CPF-(0.5)_vs_Control_Rep3
  Regulation: Regulated_by_molecule: WBMol:00003591
  Associated_with: Life_stage: WBls:0000038